Saints vs Colts 2010 Superbowl Odds, Picks & Predictions: The Indianapolis Colts [-5] are hoping their Super Bowl experience and an almost perfect season will be able to get them to their third title, as they prepare to take on the New Orleans Saints [+5]. Super Bowl XLIV will kick off at 6:30 PM ET (3:30 PM PT) from Sun Life Stadium in Miami Gardens, Florida on Sunday. The OVER/UNDER for this, Saints vs Colts 2010 Superbowl Odds, Picks & Predictions is set at a total of 57 points.

The only thing standing between Peyton Manning and his second Super Bowl title are the New Orleans Saints. But the Colts are aware that Saints supporters are spreading all over the country. Many would love to see New Orleans win their first Super Bowl title, after suffering the horrible disaster that was Hurricane Katrina, four years ago.

"A few weeks ago, a fan walked up to me and just started crying and said, 'Thank you for what you did for our city,' " said Saints receiver Robert Meachem.

But Indianapolis has its own legacy in mind. This team has the hopes to leave their mark in NFL history and become one of the NFL’s all-time greatest teams. "To get a second Super Bowl ring and having the most wins in the decade would definitely let us go down in history," said Colts LB Gary Brackett.

But it wouldn’t be football, if there weren’t injuries to report. Colts defensive end Dwight Freeney is still questionable for Sunday, as he is recovering from a torn ligament in his right ankle that occurred in the AFC Championship game. Earlier this week, Reggie Wayne had to walk off practice field due to irritation in his kneecap. As of now, this should not be a serious factor in his game.

With this Super Bowl win, the Colts would become the fifth team to hold three Super Bowl titles. Among them are the Packers, Patriots, Raiders and Redskins.

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