Denver Broncos vs. San Francisco 49ers NFL Preseason Odds Week 1: Two teams with new systems and head coaches open their NFL Preseason Odds Week 1 against each other, as the Denver Broncos travel to Candlestick Park on the East Bay to take on the San Francisco 49ers tonight at 10 PM ET (7 PM PT) on the NFL-Network.
According to NFL Preseason Odds Week 1 specialists at SportsBetting.com, the San Francisco 49ers [-3 (+105)] will go into this contest as the sports betting odds favorites in their NFL Preseason opener against the Denver Broncos [+3 (-125)] tonight. 
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For the Niners, one of the biggest questions going into this season will be: who will step up and become the starting quarterback? Earlier in the week, Frisco head coach Mike Singletary announced that Shaun Hill would be starting tonight against the Broncos. “Shaun Hill will start the game,” Singletary said. “I do not know who will start next week. Really it could have been Shaun Hill or Alex Smith. We chose Shaun Hill. Don’t read anything into it.”
Many people in the Bay Area believe that Hill has what it takes to sail this ship. “I’m just excited to get out there and play again,” Hill said. “I agree there’s no reason to read into this in any way, but obviously, my goal is to start every regular season game and go from there. I’m just excited for the opportunity.”
For the new-look Broncos, who will be celebrating their 50th NFL season, Josh McDaniels will be only the 12th NFL head coach in the franchise’s history. McDaniels is of course very well known around the league, especially for his very successful eight years and 3 Super Bowl titles as offensive coordinator for the New England Patriots (2006-08).
Also, the addition of quarterback Kyle Orton — who’s 21-12 as an NFL starter — has a lot of people exciting in the “Mile High City”. Orton comes into Denver owning the NFL’s best home record at 15-2 (.882) in his 3 years in the league. The OVER/UNDER for this Denver Broncos vs San Francisco 49ers NFL Preseason Odds Week 1 has been officially set at a combined total of 34 points scored.
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