San Francisco 49ers vs. San Diego Chargers NFL Odds Preseason Week 4: Interstate rivals collide in the final game of the NFL Odds Preseason Week 4. Tonight, beginning at 10 PM ET (7 PM PT) the San Francisco 49ers [+3½] travel way south as the sports betting odds underdogs to be defeated by the hosing favorites, San Diego Chargers [-3½] live from Qualcomm Stadium.
Unfortunately, this 49ers-Chargers game will not be televised live nationwide. However, you can still catch all the action of this California duel on Sunday at 2:30 AM ET (11:30 PM PT on Saturday), when the NFL Network airs an 
encore presentation of this NFL Odds Preseason Week 4 game. The OVER/UNDER for this, San Francisco 49ers vs. San Diego Chargers NFL Odds Preseason Week 4 has been officially set at a combined total of 36½ points scored.
Please keep in mind that the best NFL Odds Preseason Week 4 picks will be available for you from now all the way through the duration of the 2009 NFL Regular Season, 2009 NFL Playoffs, and of course, the 2010 Super Bowl XLIV in Miami, FL. However, before you move a muscle, please remember to get the latest sports betting odds for your free sports picks from the best online NFL Odds Preseason Week 4 sportsbooks in the world, courtesy of Sports-Odds.com.
For the visiting Niners, Mike Singletary is ready to lead this team towards a winning NFL season in his first full year as head coach in Frisco. This NFL Odds Preseason, Singletary got a taste for the game that is played while trying to sign rookie players/NFL Draftees and he didn’t like it one bit.
Texas Tech wide receiver, Michael Crabtree missed all of training camp and the NFL Odds Preseason because of a contract holdout. “At this point, and ever since the very beginning, my response has not changed,” said Singletary regarding the Crabtree issue. “These guys out here have been busting their tails and doing their job. It is the same scenario. If it happens, fine. If it doesn’t, we are going to keep moving forward. I’m not looking back.”
As far as the home team is concerned, Chargers coach Norv Turner has stated that he will elect to rest his star running back LaDainian Tomlinson for the NFL Odds Preseason finale against San Francisco tonight. L.T. started the first two NFL Odds Preseason games for the Bolts before sitting out last Saturday’s loss at Atlanta.
According to Turner, most of San Diego starters will see between 10 to 15 minutes of playing time tonight. However, that will not include Darren Sproles, who in the coach’s eyes has had enough touches top sit this one out entirely. "He practices at such a high level that he's ready to go play," Turner said. "Obviously he wanted to get some carries, catches and a couple returns. I think he's done that. He's had an excellent training camp, an excellent preseason and is ready to go."
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