New Orleans Saints vs. Philadelphia Eagles NFL Picks Week 2: This was supposed to be a matchup between two of the best quarterbacks in the league — Drew Brees vs. Donovan McNabb — matching each other stride for stride with their powerful offenses. Instead, it appears that only one of the headliners will be in uniform on Sunday afternoon, as this not only ruins the featured pairing, but it may also cost the host the victory.
According to NFL Picks Week 2 Betting Odds makers at SportsBook.com, the New Orleans Saints [-1½] will enter this game as the sports betting odds favorites against the McNabb-less, Philadelphia Eagles [+1½]. This NFC 
showdown is scheduled to get under way at 1 PM ET (10 AM PT) from Lincoln Financial Field in “The City that Loves you Back”, and it can be seen live on FOX.
In their last meeting back on Week 16 of the 2007 campaign, the Eagles defeated the Saints, 38-23, thanks to a 263-yard, 3-touchdown effort from Donovan McNabb. These teams have met a total of 26 times during regular season and the playoffs, with Philly holding a 16-10 advantage overall. The OVER/UNDER for this, New Orleans Saints vs. Philadelphia Eagles NFL Picks Week 2 game has been speculated to end up at a combined 46 points total.
In Week 1, we all witnessed how the Eagles held their collective breaths hen McNabb didn’t get up after scoring a rushing touchdown in a one-sided victory at Carolina. The Eagles defense came up huge against the Panthers, with a whopping 7 turnovers. Philadelphia is certainly going to need a whole lot more where that came from, as the NFL most powerful offense will be in full display in this one.
In the Saints season opener, quarterback Drew Brees send a message to the league, that if you’re going to take on this team, you better pack a lunch! In the first game of the year, Brees was surgical with his precision passing (26-of-34 for a ridiculous 358 yards), on the way to an all-time NFL record, 6-touchdowns in the opening week, as N.O. just dismantled Detroit, 45-27.
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