Indianapolis Colts (1-2) at Houston Texans (0-3) Betting Odds: Peyton Manning, and the struggling Indianapolis Colts will try to take full advantage of a vulnerable, and thus far, win-less Houston Texans team, as they try to regain their swagger going forward. This is certainly unfamiliar territory for Indianapolis, as they’re off to their worst start since losing the first four games of the 1998 season.

Going into Week 5, and according to odds-makers at BetUS.com, the Indianapolis Colts are slight -3 NFL Week 5 Online Sports Betting Odds favorites against the Houston Texans (+3).  

Earlier this week, QB Peyton Manning took the blame for the team’s uncharacteristic woes at the start of this NFL season.

“(The mistakes) are definitely correctable,” Manning said. “It’s just a little thing here or there. Coach Dungy points this out a lot, but those little things here or there are enough to get you beat.

He always talks about what else is going on around the league, how there are some teams that are 3-0 that a play here or a play here, they could be 1-2 or 0-3.There’s a play here and a play there where we could be 3-0, but we’re not and there’s a reason for that. We need to earn those plays and everybody needs to raise their level of play a little bit. As far as I’m concerned, that starts with me.”

The Colts are currently (in 3rd place) just above the Houston Texans in the AFC South Standings. The Houston Texans will be looking for their first win of the NFL season when they host Manning and the Colts on Sunday at 1 PM ET.

The Texans will be returning home for the first time all year long, after being forced out of Reliant Stadium due to the damages caused by Hurricane Ike in early September. Indy is 5-1 all time at Reliant Stadium. The OVER/UNDER for this AFC South battle between the Indianapolis Colts at Houston Texans has been set at a combined total of 47 points.

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